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Young Adult Science Cafe: Antibiotic-Resistant Bacteria
March 30, 2017 @ 5:00 pm - 7:00 pmFree
Dr. Daniel Nelson is an Associate Professor and Head of the Laboratory of Antimicrobial Discovery at the University of Maryland. He has a joint appointment in the Department of Veterinary Medicine on the main College Park campus and at the Institute for Bioscience and Biotechnology Research in Rockville, where his laboratory is located.
Dr. Nelson will discuss his background and provide a historical perspective on antibiotics. He will share his expert insight regarding antibiotic resistant bacteria, antibiotics in animal feed, current antibiotic initiatives and legislation, alternatives to antibiotics, and the reason why drug companies are getting out of the antibiotic business.
Food and Refreshments will be provided.
About our Speaker
Dr. Nelson’s research interests focus on studying bacterial pathogenesis, bacterial biofilms, and development of bacteriophage-derived proteins as novel antimicrobial agents. The largest part of his research is centered on proteins that are part of the bacteriophage lytic system. These proteins, known as endolysins, have the ability to rapidly bind to and degrade the bacterial cell wall. As such, they represent an alternative approach to conventional antibiotics. In 2001, while a postdoctoral fellow at The Rockefeller University in New York City, Dr. Nelson conducted the first study that demonstrated in vivo efficacy of an endolysin against a bacterial infection. The next five years represented a tremendous expansion in the discovery of new endolysins as well as studies aimed at evaluation of host-range, resistance, toxicity, synergy, pharmacokinetics, and additional in vivo models. Currently, several biotechnology and pharmaceutical companies have licensed some of the endolysin technology and human clinical trials are progressing. In 2007, Dr. Nelson moved to the University of Maryland where his laboratory began to focus on structure/function studies for several of the more active endolysins. Based on this knowledge, his group is now generating endolysins with more desirable attributes, such as higher activity, an expanded host range, or a more favorable thermostability profile. It is anticipated that these bioengineering approaches will result in the development of the next generation endolysins with enhanced properties.
Dr. Nelson regularly serves on various scientific study sections for the National Institutes of Health, is a Department of Defense subject matter expert for antibiotic resistance, and consults or collaborates with several public and private companies interested in antimicrobial technologies.
About the event:
Date: Thursday, March 30, 2017
Time: 5:00 pm – 7:00 pm
Location: Room 2230, Building III, The Universities at Shady Grove, 9630 Gudelsky Dr, Rockville, MD 20850.
Target Audience: Middle School and High School Students (Parents are encouraged to attend)
Hosted By: The American Society for Biochemistry and Molecular Biology Student Chapter of USG in affiliation with the Rockville Science Center.
The event will be Live Streamed on the USG ASBMB-UAN Youtube Channel from 5:00 – 7:00. Follow the link at 5:00 pm on Thursday, March 30, 2017. A YouTube account is not needed to watch the event. To ask the presenter questions during the event while watching live, you must log-in to your YouTube account. Please Like, Share, and Subscribe to the USG ASBMB-UAN YouTube Channel if you enjoy the event, and give us your feedback in the comments section below.